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| Catalog: | C-FC-0930A |
| Product Type: | FCM Antibody |
| Size: | 50 μg/100 μg |
| Reactivity: | Mouse |
| Analysis mode: | FCM |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Alternate names: | Thy-1.2 membrane glycoprotein,Thy1.2,Thy-1.2 antigen,CD90.2,Thy-1.2 |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | Biotin |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P01831 |
| Clone NO.: | 30H12 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Core Diagnostic Capabilities
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