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| Catalog: | C-FC-0870A |
| Product Type: | FCM Antibody |
| Size: | 25 μg/100 μg |
| Reactivity: | Human |
| Analysis mode: | FCM |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Alternate names: | Integrin alpha-Iib,ITGA2B,GPalpha Iib,GPIIb,Platelet membrane glycoprotein Iib,CD41,GP2B, ITGAB |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | Biotin |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P08514 |
| Clone NO.: | HIP8 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.
Core Diagnostic Capabilities
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