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| Catalog: | C0658A |
| Product Type: | Antibody |
| Analysis mode: | WB, IP, IHC, IF, FC, CoIP, ELISA |
| Species specificity: | Human, pig, rat, swine |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Isotype: | IgG2b |
| Concentration: | 1000 μg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3 |
| Purification method: | Protein A purification |
| Conjugation: | Unconjugated |
| Immunogen: | BCL2 |
| Genn_ID: | 596 |
| Gene accession: | BC027258 |
BCL2 belongs to the Bcl-2 family. It inhibits apoptosis in a variety of cell systems, including factor-dependent lymphohematopoiesis and nerve cells. BCL2 regulates cell death by controlling the permeability of the mitochondrial membrane. It seems to play a role in the caspase feedback loop system. BCL2 inhibits caspase activity by preventing mitochondria from releasing cytochrome c and/or binding to activator of apoptosis (APAF-1).
Diagnostic Development
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