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| Catalog: | C0351A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | BCL2 |
| Swiss port: | P10415 |
| Gene accession: | NP000624 |
| Celluar localization: | Mitochondrion outer membrane, Nucleus membrane, Endoplasmic reticulum membrane |
| Tissue specificity: | Expressed in a variety of tissues. |
It is also called B cell leukemia/lymphoma 2. This gene encodes a complete external mitochondrial membrane protein that can prevent the apoptotic death of some cells, such as lymphocytes. Constitutive expression of BCL2, such as the translocation of BCL2 to the Ig heavy chain site, is believed to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, with different c-terminals
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