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| Catalog: | C0350A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,IHC-p |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4 |
| Purification method: | Protein A purification |
| Application: | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | Bcl-2 |
| Swiss port: | P10415 |
| Celluar localization: | Mitochondrion outer membrane, Nucleus membrane, Endoplasmic reticulum membrane |
| Tissue specificity: | Expressed in a variety of tissues. |
It is also called B cell leukemia/lymphoma 2, which inhibits apoptosis in a variety of cell systems, including factor-dependent lymphohematopoiesis and nerve cells. Regulate cell death by controlling mitochondrial membrane permeability. Play a role in the caspase feedback loop system. Inhibits caspase activity by preventing the release of cytochrome c from mitochondria and/or binding to activator of apoptosis (APAF-1).
Diagnostic Development
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