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| Catalog: | C-FC-0762A |
| Product Type: | FCM Antibody |
| Size: | 20 tests/50 tests/100 tests/200 tests |
| Reactivity: | Mouse |
| Analysis mode: | ICFCM |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Alternate names: | Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | APC |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P18893 |
| Clone NO.: | JES5-16E3 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.
Core Diagnostic Capabilities
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