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| Catalog: | C-FC-0624A |
| Product Type: | FCM Antibody |
| Size: | 25 μg/50 μg/100 μg/200 μg |
| Reactivity: | Human, Mouse |
| Analysis mode: | ICFCM |
| Host: | Rat |
| Isotype: | Rat IgG1, κ |
| Alternate names: | Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | APC |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P05113,P04401 |
| Clone NO.: | TRFK5 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment. |
IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.
Core Diagnostic Capabilities
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