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| Catalog: | C-FC-0528A |
| Product Type: | FCM Antibody |
| Size: | 20 tests/50 tests/100 tests/200 tests |
| Reactivity: | Human |
| Analysis mode: | FCM |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Alternate names: | Prominin-1, PROM1, AC133 |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | APC |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | O43490 |
| Clone NO.: | W6B3C1 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD138 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cs and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.1
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