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| Catalog: | C0771A |
| Product Type: | Antibody |
| Size: | 100µg |
| Analysis mode: | ELISA, WB, IF, IP |
| Species specificity: | Human |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
| Purification method: | Immunogen affinity purified |
| Conjugation: | Unconjugated |
| Immunogen: | FANCI |
| Swiss port: | Q9NVI1 |
FANCI repairs DNA double-strand breaks through homologous recombination, and promotes FANCD2 single-alkylation through FANCL, participates in DNA repair site recruitment, and plays an important role in the repair of inter-strand DNA cross-links (ICLs). It is used to maintain the stability of chromosomes. Specific binding to branched DNA: Combining single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA), involved in S phase and G2 phase checkpoint activation after DNA damage.
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