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| Catalog: | C-FC-2997A |
| Product Type: | FCM Antibody |
| Size: | 50 µL/100 µL/200 µL |
| Reactivity: | Human |
| Specificity: | Human CD31 |
| Analysis mode: | IHC-P,FCM |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Alternate names: | platelet/endothelial cell adhesion molecule 1 |
| Form: | Liquid |
| Shipping: | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Purification method: | Protein A |
| Conjugation: | Unconjugated |
| Immunogen: | Recombinant Human CD31 / PECAM-1 protein |
| Buffer: | 0.2 μm filtered solution in PBS |
| Application: | Hemangioblast Markers; ITIM/ITAM Immunoreceptors and Related Molecules |
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Core Diagnostic Capabilities
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