Catalog: | C-FC-2846A |
Product Type: | FCM Antibody |
Size: | 50 µL/100 µL/200 µL |
Reactivity: | Human |
Specificity: | Human BMP-2 |
Analysis mode: | FCM,ICC/IF |
Host: | Mouse |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Alternate names: | bone morphogenetic protein 2 |
Form: | Liquid |
Shipping: | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Purification method: | Protein A |
Conjugation: | Unconjugated |
Immunogen: | Recombinant Human BMP-2 protein |
Buffer: | 0.2 μm filtered solution in PBS |
Application: | Early Mesodermal Lineage Markers |
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
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