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| Catalog: | C0578A |
| Product Type: | Antibody |
| Reactivity: | M,R |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% Proclin300, 50% glycerol, pH7.3 |
| Purification method: | Antigen Affinity Purification |
| Application: | Cardiovascular |
| Conjugation: | Unconjugated |
| Immunogen: | ANGPT2 |
| Swiss port: | O15123 |
| Celluar localization: | Secreted |
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial cell TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants of this gene have been found to encode three different subtypes.
Diagnostic Development
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