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AFP polyclonal antibody

  • Product Information
  • Description
Catalog: C0266A
Product Type: Antibody
Reactivity: H,M
Analysis mode: WB,IHC
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: Cancer, Cardiovascular, Developmental Biology
Conjugation: Unconjugated
Immunogen: AFP
Swiss port: P02771
Genn_ID: 174
Celluar localization: Secreted

The gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and liver during the fetal period. The expression of alpha-fetoprotein in adults is often associated with liver cancer or teratoma. However, the inheritance of alpha-fetoprotein can also be found in individuals without obvious pathology. This protein is considered to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes exist simultaneously in the same transcription direction on chromosome 4. Alpha-fetoprotein exists in monomers, dimers and trimers, and can bind copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in the amniotic fluid is used to determine renal loss of protein to screen for spina bifida and anencephaly.

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Diagnostic Development

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