Catalog: | C0262A |
Product Type: | Antibody |
Reactivity: | H,M |
Analysis mode: | IHC,IF |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
Purification method: | Affinity purification |
Application: | Cancer, Cardiovascular, Developmental Biology |
Conjugation: | Unconjugated |
Immunogen: | AFP |
Swiss port: | P02772 |
Genn_ID: | 11576 |
Celluar localization: | Secreted |
Tissue specificity: | Plasma.Highest expression level in embryo. |
The gene encodes alpha-fetoprotein, which is a major plasma protein produced by the yolk sac and liver during the fetal period. The expression of alpha-fetoprotein in adults is often associated with liver cancer or teratoma. However, the inheritance of alpha-fetoprotein can also be found in individuals without obvious pathology. This protein is considered to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes exist simultaneously in the same transcription direction on chromosome 4. Alpha-fetoprotein exists in monomers, dimers and trimers, and can bind copper, nickel, fatty acids and bilirubin.
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