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AF647 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody

  • Product Information
  • Description
Catalog: C-FC-0468A
Product Type: FCM Antibody
Size: 25μg/50μg/100μg
Reactivity: Mouse
Analysis mode: FCM
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: Gr-1,Gr1,Ly-6G/Ly-6C,Ly6G/Ly6C
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P35461,P0CW02,P0CW03
Clone NO.: RB6-8C5
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment.

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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