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| Catalog: | C-FC-0476A |
| Product Type: | FCM Antibody |
| Size: | 50 tests/100 tests/200 tests/500 tests |
| Reactivity: | Mouse/Human |
| Analysis mode: | FCM |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Alternate names: | Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | AF647 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P05555,P11215 |
| Clone NO.: | M1/70 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Core Diagnostic Capabilities
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