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| Catalog: | C-FC-0475A |
| Product Type: | FCM Antibody |
| Size: | 25μg/50μg/100μg |
| Reactivity: | Human, Mouse |
| Analysis mode: | FCM |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Alternate names: | Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | AF647 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P05555,P11215 |
| Clone NO.: | M1/70 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment. |
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Core Diagnostic Capabilities
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