Catalog: | C-FC-0321A |
Product Type: | FCM Antibody |
Size: | 20 tests/50 tests/100 tests/200 tests |
Reactivity: | Human |
Analysis mode: | FCM |
Host: | Mouse |
Isotype: | Mouse IgG1, κ |
Alternate names: | T6, R4,CD 1a,CD1A ,T-cell surface glycoprotein CD1a |
Form: | Liquid |
Shipping: | Biological ice pack at 4℃ |
Storage: | 2-8℃ |
Conjugation: | AF647 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Swiss port: | P06126 |
Clone NO.: | OKT-6 |
Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.
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