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AF647 Anti-Human CD123 Antibody

  • Product Information
  • Description
Catalog: C-FC-0308A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Human
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: IL-3Rα, IL-3 Receptor alpha
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P26951
Clone NO.: 6H6
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

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