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| Catalog: | C-FC-0304A |
| Product Type: | FCM Antibody |
| Size: | 20 tests/50 tests/100 tests/200 tests |
| Reactivity: | Human |
| Analysis mode: | FCM |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Alternate names: | Integrin alpha-L,LFA-1A,CD11A,ITGAL |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | AF647 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P20701 |
| Clone NO.: | R7-1 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Core Diagnostic Capabilities
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