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AF488 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody

  • Product Information
  • Description
Catalog: C-FC-0262A
Product Type: FCM Antibody
Size: 50 tests/100 tests/200 tests/500 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: Gr-1,Gr1,Ly-6G/Ly-6C,Ly6G/Ly6C
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P35461,P0CW02,P0CW03
Clone NO.: RB6-8C5
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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