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AF488 Anti-Mouse CD3ε Antibody

  • Product Information
  • Description
Catalog: C-FC-0216A
Product Type: FCM Antibody
Size: 25μg/50μg/100μg
Reactivity: Mouse
Analysis mode: FCM
Host: Armenian Hamster
Isotype: Armenian Hamster IgG
Alternate names: T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P22646
Clone NO.: 145-2C11
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment.

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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