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AF488 Anti-Mouse CD183/CXCR3 Antibody

  • Product Information
  • Description
Catalog: C-FC-0197A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Armenian Hamster
Isotype: Armenian Hamster IgG
Alternate names: C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: O88410
Clone NO.: CXCR3-173
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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