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| Catalog: | C-FC-0076A |
| Product Type: | FCM Antibody |
| Size: | 50 μg/500 μg/1 mg |
| Reactivity: | Mouse |
| Analysis mode: | Depletion, FCM, WB, IHC, IP |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Alternate names: | Gr-1,Gr1,Ly-6G/Ly-6C,Ly6G/Ly6C |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | None (Purified antibody/Azide Free/Low endotoxin) |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Swiss port: | P35461,P0CW02,P0CW03 |
| Clone NO.: | RB6-8C5 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.1 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.
Core Diagnostic Capabilities
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