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AF/LE Purified Anti-Mouse CD3 Antibody

  • Product Information
  • Description
Catalog: C-FC-0049A
Product Type: FCM Antibody
Size: 50 μg/500 μg/1 mg
Reactivity: Mouse
Analysis mode: FCM,IHC-F,IP,ICC
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain,CD3E/D/G/Z,CD3e/d/g/z,CD3E/D/G/Z,CD3
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: None (Purified antibody/Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swiss port: P04235,P11942,P22646,P24161,P29020
Clone NO.: 17A2
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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