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| Catalog: | C-FC-0041A |
| Product Type: | FCM Antibody |
| Size: | 50 μg/500 μg/1 mg |
| Reactivity: | Mouse |
| Analysis mode: | FCM,WB,Block |
| Host: | Rat |
| Isotype: | Rat IgG1, κ |
| Alternate names: | Interleukin-10 receptor subunit alpha,Il10ra,IL-10 receptor subunit alpha, IL-10R subunit alpha,IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1,CD210,Il10ra |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | None (Purified antibody/Azide Free/Low endotoxin) |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Swiss port: | Q61727 |
| Clone NO.: | 1B1.3A |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.
Core Diagnostic Capabilities
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