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| Catalog: | C-FC-0036A |
| Product Type: | FCM Antibody |
| Size: | 50 μg/500 μg/1 mg |
| Reactivity: | Mouse |
| Analysis mode: | FCM,WB,IHC,IP |
| Host: | Rat |
| Isotype: | Rat IgG2a, κ |
| Alternate names: | Integrin beta-2,Itgb2,Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta,Complement receptor C3 subunit beta,CD18 |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | None (Purified antibody/Azide Free/Low endotoxin) |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Swiss port: | P11835 |
| Clone NO.: | M18/2 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.
Core Diagnostic Capabilities
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