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AF/LE Purified Anti-Human IL-4 Antibody

  • Product Information
  • Description
Catalog: C-FC-0020A
Product Type: FCM Antibody
Size: 50 μg/500 μg/1 mg
Reactivity: Human
Analysis mode: Neut, ICFCM, IHC
Host: Rat
Isotype: Rat IgG1, κ
Alternate names: Interleukin-4,IL-4,B-cell IgG differentiation factor,B-cell growth factor 1,BSF-1,IGG1 induction factor
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: None (Purified antibody/Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swiss port: P05112
Clone NO.: MP4-25D2
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

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