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AF/LE Purified Anti-Human CD44 Antibody

  • Product Information
  • Description
Catalog: C-FC-0014A
Product Type: FCM Antibody
Size: 50 μg/500 μg/1 mg
Reactivity: Human
Analysis mode: Block, FCM, WB, IF
Host: Rat
Isotype: Rat IgG2a, κ
Alternate names: LHR,PGP-I,CDw44,Epican,HUTCH-I
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: None (Purified antibody/Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swiss port: P16070
Clone NO.: Hermes-1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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