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AF/LE Purified Anti-Human CD3 Antibody

  • Product Information
  • Description
Catalog: C-FC-0011A
Product Type: FCM Antibody
Size: 50 μg/500 μg/1 mg
Reactivity: Human
Analysis mode: Activ, Depletion, Inhibition, FCM, IHC
Host: Mouse
Isotype: Mouse IgG2a, κ
Alternate names: T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: None (Purified antibody/Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swiss port: P07766
Clone NO.: OKT3
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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