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AF/LE Purified Anti-Human CD1a Antibody

  • Product Information
  • Description
Catalog: C-FC-0003A
Product Type: FCM Antibody
Size: 50 μg/500 μg/1 mg
Reactivity: Human
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: T6, R4,CD 1a,CD1A ,T-cell surface glycoprotein CD1a
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: None (Purified antibody/Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swiss port: P06126
Clone NO.: OKT-6
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.

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