Catalog: | C0264A |
Product Type: | Antibody |
Reactivity: | H,M |
Analysis mode: | WB,IHC |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 0.02 mg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
Purification method: | Affinity purification |
Application: | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Conjugation: | Unconjugated |
Immunogen: | ADIPOQ |
Swiss port: | Q60994 |
Genn_ID: | 11450 |
Celluar localization: | Secreted |
Tissue specificity: | Synthesized exclusively by adipocytes and secreted into plasma.Highest expression level in subcutaneous adipose tissue. |
Adiponectin (AdipoQ) is a hormone derived from fat cells and one of the most abundant adipokines in blood circulation. Adiponectin regulates many metabolic processes, including improving insulin sensitivity and anti-inflammatory activity. Adiponectin works by binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2, to activate a series of different signaling molecules. AdipoR1 is mainly expressed in skeletal muscle, while AdipoR2 is mainly expressed in the liver. AdipoQ may play a role in cell growth, angiogenesis and tissue remodeling by binding and isolating various growth factors.
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