Catalog: | C0865T |
Product Type: | Test kit |
Unit: | 96 tests |
Regulatory status: | RUO |
Priciple: | Sandwich ELISA |
Assay time: | 3 hours |
Limit of detection: | 0.079 ng/ml |
Sample type: | Serum |
Sample requirements: | 10 µl/test |
Analysis mode: | ELISA |
Species specificity: | Mouse |
Storage: | 2–8°C |
Application: | Chronic renal failure, Coronary artery disease, Diabetology - Other Relevant Products, Energy metabolism and body weight regulation, Animal studies |
Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 aminoacid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells (adipokine). Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation. It inhibits the inflammatory processes of atherosclerosis suppressing the expression of adhesion and cytokine molecules in vascular endothelial cells and macrophages, respectively. This adipokine plays a role as a scaffold of newly formed collagen in myocardial remodelling after ischaemic injury and also stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signalling in endothelial cells.
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