Catalog: | C0817T |
Product Type: | Test kit |
Unit: | 96 tests |
Regulatory status: | RUO |
Incubation time: | 1 x 1 h, 1 x overnight at 4°C, 1 x at RT |
Standard range: | 2-250 pg/mL |
Sample requirements: | 100 µL |
Isotope/Substrate: | ER 405-414 nm |
Analysis mode: | ELISA |
Application: | Metabolic Syndrome |
In addition to GH-releasing properties and its orexant action, Ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into Ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3 by GOAT (Ghrelin Octanoyl Acyl Transferase). This step is essential for biological activity making GOAT a perfect target for drugs in feeding behaviour.
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